[ChemFaces 한국공식대리점] Notoginsenoside R1

[ChemFaces 한국공식대리점] Notoginsenoside R1

[Notoginsenoside R1]

Description:

Notoginsenoside R1(NR1) is the main ingredient with cardiovascular activity in Panax notoginseng, which has some neuronal protective, antihypertensive,antioxidant, anti-inflammatory, antiapoptotic, and immune-stimulatory activities. NR1 can counteract endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo.

NR1 inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways, it attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation.

Product Information:
CAS No.:	80418-24-2
Catalog No.:	CFN99999
Molecular Formula:	C47H80O18
Molecular Weight:	933.13 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	White powder
Source:	The roots of Panax notoginseng (Burk.)F.H.Chen
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.